Objekt-Metadaten

Chronic Diarrhea in Dogs – Retrospective Study in 136 Cases
Volkmann, M. ;  Steiner, J. M. ;  Fosgate, G. T. ;  Zentek, J. ;  Hartmann, S. ;  Kohn, B.

HaupttitelChronic Diarrhea in Dogs – Retrospective Study in 136 Cases
AutorVolkmann, M.
AutorSteiner, J. M.
AutorFosgate, G. T.
AutorZentek, J.
AutorHartmann, S.
AutorKohn, B.
Seitenzahl13 S.
DDC630 Landwirtschaft, Veterinärmedizin
Auch erschienen inJournal of Veterinary Internal Medicine. - 31 (2017), 4, S. 1043–1055
ZusammenfassungBackground

Chronic diarrhea (CD) is common in dogs, and information on frequency and distribution of primary and secondary causes is lacking.

Objectives

To evaluate underlying causes and predictors of outcome in dogs with CD.

Animals

One hundred and thirty-six client-owned dogs with CD (≥3 weeks duration).

Methods

Retrospective review of medical records (Small Animal Clinic, Freie Universität Berlin, Germany, 09/2009-07/2011). Quantification of final diagnoses and comparison of clinical aspects including disease severity and clinicopathological abnormalities among dogs with clinical remission (either complete [gastrointestinal signs absent] or partial [clinical improvement of gastrointestinal signs and reduced episodes with shortened duration]), and those without recovery.

Results

Ninety percent of dogs were diagnosed with a primary enteropathy: inflammatory (71%; of those 66% dietary responsive, 23% idiopathic, 11% antibiotic responsive), infectious (13%), neoplastic (4%), and in one dog each mechanical disease or systemic vasculitis. Secondary causes were diagnosed in 10% of dogs: exocrine pancreatic (6%), endocrine (2%), and in one dog each hepatic, renal, and cardiac disease. In total, 87% of dogs had clinical remission, whereas 13% died or did not respond to treatment: Lack of recovery was frequently recorded for dogs with primary inflammatory (idiopathic) or neoplastic disease and was significantly associated with increased disease severity scores (P = .005), anemia (hematocrit < 40%, P < .001), severe hypoalbuminemia (serum albumin <2.0 g/dL, P = .008), and severe hypocobalaminemia (serum cobalamin concentration <200 pg/mL, P = .006).

Conclusions and clinical importance

Inflammatory enteropathies and particularly those of dietary origin were the most common causes of CD in dogs. Findings support the usefulness of hematocrit, and serum albumin and cobalamin concentration as prognostic markers in dogs with CD.
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Fachbereich/EinrichtungFB Veterinärmedizin
Erscheinungsjahr2017
Dokumententyp/-SammlungenWissenschaftlicher Artikel
SpracheEnglisch
RechteCreative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Anmerkungen des AutorsDer Artikel wurde in einer reinen Open-Access-Zeitschrift publiziert.
Erstellt am28.09.2017 - 10:26:44
Letzte Änderung28.09.2017 - 10:27:26
 
Statische URLhttp://edocs.fu-berlin.de/docs/receive/FUDOCS_document_000000028048
DOI10.1111/jvim.14739
Zugriffsstatistik
 

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