Holtgrewe, Manuel ;  Universität <Berlin, Freie Universität> / Fachbereich Mathematik und Informatik

Main titleMason
Subtitlea read simulator for second generation sequencing data
AuthorHoltgrewe, Manuel
InstitutionUniversität <Berlin, Freie Universität> / Fachbereich Mathematik und Informatik
No. of Pages18 S.
Series Freie Universität Berlin, Fachbereich Mathematik und Informatik : Ser. B, Informatik ; [20]10,06
Keywordsread mapping; second generation sequencing; simulation
Classification (DDC)005 Computer programming, programs, data
AbstractWe present a read simulator software for Illumina, 454 and Sanger reads. Its features include position specific error rates and base quality values. For Illumina reads, we give a comprehensive analysis with empirical data for the error and quality model. For the other technologies, we use models from the literature. It has been written with performance in mind and can sample reads from large genomes. The C++ source code is extensible, and freely available under the GPL/LGPL.
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FU DepartmentDepartment of Mathematics and Computer Science
Other affiliation(s)Insitut für Informatik
Year of publication2010
Type of documentBook
Terms of use/Rights Nutzungsbedingungen
Created at2010-09-29 : 09:48:19
Last changed2015-02-27 : 08:25:38
Static URLhttp://edocs.fu-berlin.de/docs/receive/FUDOCS_document_000000006687